The map's events are set following the nuclear explosion after a multiplayer game ends on the multiplayer map from Call of Duty: Black Ops, Nuketown, with buildings and other environments demolished as well as the nuclear fireball of a 'mushroom' cloud seen outside the map. The map's main playable factions are the CIA and CDC. It is based on Nuketown, a multiplayer map from Call of Duty: Black Ops and Call of Duty: Black Ops II.

Nuketown Zombies, also known as Nuketown in-game, and Nuke'dTown Zombies! in concept art, is a Zombies map that is featured in Call of Duty: Black Ops II, and the thirteenth Zombies map overall. Upon arrival in Nuketown the agents lose communication with Hangar 18 and become strandedвЂ¦setting the stage for Nuketown Zombies.' - Season Pass map description The zombie soldiers attack the radiation scientists and turn them, and after receiving a distress signal, the base in Nevada sends in CIA and CDC agents to investigate. A group of radiation scientists are investigating the Nuketown remains and discover soldiers that have been revived by Element 115 from a nearby Nevada base. ' Nuketown Zombies is set during the events of Moon, and after the end of the multiplayer level from the original Black Ops game.

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